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TUCSON, ARIZ. — Preliminary results from a genomic study of patients infected by the hepatitis C virus suggest that a polymorphism in the interferon receptor promoter region could be a biomarker for predicting who will develop depression when treated with interferon-based therapies and ribavirin.

The polymorphism, -408 C/T, was present in 23 of 60 patients, Dr. Muhamad Aly Rifai reported at the annual meeting of the Academy of Psychosomatic Medicine. All but two patients with the polymorphism developed depression. No patient without -408 C/T had the mood disorder.

"This is …

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