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Virtually half of England is now under restrictions that prevent animal movement within a zone that stretches from Lincolnshire to Sussex.

The Prime Minister, Gordon Brown, said yesterday said that there were now 11 cases of bluetongue. There have also been reports of unconfirmed cases of the midge-spread disease in Norfolk, Essex, Cambridgeshire and the East Midlands. Seven cases of foot and mouth have been reported in recent weeks.

Mr Brown told farmers: “We are taking all the action that is necessary within a protected zone.” The Government was “absolutely determined to stamp out the disease, to contain, control and eradicate it”. Environment, Food and Rural Affairs Secretary, Hilary Benn, will consider possible compensation to farmers.

The entire country is now viewed by the Government as being at risk of either bluetongue or foot and mouth. Farmers in Essex are under the greatest restrictions, with Defra describing the county as a “combined zone” due to the threat posed by the two viruses.

“We are talking about two of the great animal plagues of all time,” according to Professor Peter Mertens, a bluetongue expert. “To have one is unfortunate, but to have two in the same month is a disaster.”

A National Farmers’ Union spokesman said: “Farmers are punch- drunk at the news.” JO

Copyright c 2007 Independent Newspapers UK Limited. All rights
owned or operated by The Independent.
Provided by ProQuest Information and Learning Company. All rights Reserved.

Information provided by: Findarticles.com

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SAN LEANDRO — Officials have confirmed the first case of West Nile virus in the city this year after a dead squirrel was found infected with the disease.

On Sept. 18, a resident alerted authorities to the dead rodent, which had been discovered on the 200 block of Cambridge Avenue. The Alameda County Mosquito Abatement District this week determined the squirrel had been infected with West Nile.

Officials said the finding should not be a cause for alarm. No other infected squirrels or birds have been found in the city this year, although several cases of the virus have been reported in surrounding counties.

“Generally speaking, there have been very low infection rates,” said Mosquito Abatement District Manager John Rusmisel. “We’re trying to see how much density there is in the area, which so far looks to be pretty low. If there are any other positive (cases) out there, we haven’t found anything yet.”

This is not the first time West Nile virus has been reported in San Leandro. In 2004, an infected squirrel was discovered near Wicks Boulevard and the flood control channel.

Also, two people from San Leandro have been infected with West Nile in the past, but both contracted the virus outside the area.

In Hayward and Castro Valley, two infected squirrels have been found this year. Most cases, however, are usually isolated to the Tri-Valley area.

This year, the abatement district also has reported 15 dead birds infected with the virus.

In the meantime, the abatement district is inspecting known mosquito sources and stagnant pools in San Leandro and has sent specimens for testing to the Center for Vectorborne Diseases at the University of California, Davis, Rusmisel said.

“Chances are this is going to be an isolated incident,” he said. “But we’re going to make sure it is by doing a lot more work on our own.”

While West Nile typically has been found in birds and other animals, it is not uncommon for the virus to affect squirrels, particularly tree squirrels, according to the California Department of Public Health’s Web site.

Infected tree squirrels may display abnormal neurological signs that make it obvious they have the virus, including uncoordinated movement, paralysis, shaking or circling, according to the department.

But if a squirrel has these signs, it doesn’t necessarily mean it became infected by a mosquito, the Web site states.

People can’t become infected with West Nile by being near an infected squirrel. However, dead squirrels with the virus indicate there could be infected mosquitoes nearby, and authorities warn people to use protective clothing and repellent and to remove standing water at their homes where mosquitoes can breed.

Reach Martin Ricard at mricard@bayareanewsgroup.com.

c2007 ANG Newspapers. Cannot be used or repurposed without prior
written permission.
Provided by ProQuest Information and Learning Company. All rights Reserved.

Information provided by: Findarticles.com

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Bird Flu Virus Can Infect Fetus

September 28, 2007

The deadly H5N1 bird flu virus can pass through the placenta of pregnant women and into the fetus, Chinese scientists report.

They also discovered that the virus infects organs other than lungs in adults.

a man and a pregnant women — killed by bird flu, to determine how the virus affects different body organs.

They detected H5N1 genetic material and antigens in the lungs, certain cells in the trachea, the T-cells of the lymph node, neurons in the brain, and in cells of the placenta. They also found H5N1 genetic material in the intestinal mucosa but did not find any antigens there.

The dead woman’s fetus had H5N1 genetic material and antigens in the lungs, circulating cells …


Read the full article with a Free Trial at MyWire.

Information provided by: Findarticles.com

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MessageLabs, the leading provider
of integrated messaging and web security services to businesses worldwide,
today announced the results of its MessageLabs Intelligence Report for
September and 3rd quarter of 2007. The new data reveals that virus and
phishing levels have significantly increased, reaching levels not seen
since early 2006. In addition, MessageLabs exposes a second wave of highly
targeted C-level and senior management email attacks with increased
sophistication and outreach.

With a virus threat now incorporated within every 48 emails,
cyber-criminals are steering away from using the more obvious attachment
method of distribution and favoring the use of links to malicious websites
hosting malware code. This technique, which increased in popularity by
approximately 15 percent this quarter, enables social engineering-based
attacks such as e-postcards to be utilized.

Mirroring the recent resurgence in virus attacks, the volume of phishing
threats has also reached exponential levels this month with every 87 emails
comprising of a phishing attack. Through the increased availability of
phishing kits and the uptake of aggressive phishing techniques such as
‘rock’ phishing, the quantity and severity of these attacks are able to
increase dramatically. ‘Rock’ phishing utilizes a phishing kit, which
enables a single compromised computer within a botnet to host multiple
phishing sites at the same time.

“The start of the new school year seemed to bring back an increase in
old-school threats and in high volumes. With email more ubiquitous than the
telephone and one in 48 emails containing a virus, most people are
unwittingly receiving more than one virus a day,” said Mark Sunner, Chief
Security Analyst, MessageLabs. “As we enter the last quarter of 2007 and
draw closer to the holiday season, the bad guys will be provided
opportunity to disguise their attacks through the increase in genuine
well-wishing emails and the anticipated upsurge in online shopping traffic.
In addition, with the incessant rise of comprised machines through
aggressive botnet activity, further spam level increases are anticipated.”

September is not just the month of mass-outreach attacks — the highly
targeted approach is still rife. On September 12, more than 1,100 C-level
and senior management executives became the target of another attack,
thought to be from the same perpetrators of the June 26 C-level assault.
With increased sophistication, the emails, which purport to be from a
recruitment company, use a Microsoft error message to persuade the victims
to click on the RFT attachment. Once opened, the RFT file contains an
executable, which drops two files onto the computer which in turn will be
used to pass sensitive information back to the attacker.

Other report highlights:

Web Security: Analysis shows that 73.8 percent of the malware intercepted
in September was new. Analysis of policy-based traffic highlighted that
corporate tolerance of social networking sites is diminishing with Facebook
being the most blocked site within the Personal’s and Dating category for
SMBs and Friends Reunited top of the same category for the Enterprise.

Spam: In September, the global ratio of spam in email traffic from new and
unknown bad sources, for which the recipient addresses were deemed valid,
was 73.5 percent, a decrease of 0.5 percent on the previous month. When
reviewing the overall spam rates on a quarterly basis, a drop of 0.9
percent was observed since Q2 2007.

Viruses: This month, the global ratio of viruses in email traffic from new
and previously unknown bad sources destined for valid recipients was 1 in
48.8 emails (2.05 percent), an increase of 0.8 percent since last month.
Virus and trojan levels have declined steadily since 2006, with the Q3 2007
rates of 1 in 67.2 emails being the highest quarterly level since Q2 2006.

Phishing: With an increase of 0.6 percent, one in 87.2 emails is comprised
of some form of phishing attack in September, the highest level to date.
When judged as a proportion of all email-borne threats such as viruses and
trojans, the number of phishing emails has risen by 9.7 percent to 56.0
percent of the malware threats intercepted in September. Over the last
quarter, phishing rates have increased from 1 in 232.0 to 1 in 124.3.

Geographical Trends:

--  Israel continued to have the highest spam rate this month with 73.8
    percent. Hong Kong was the second most highly spammed country registering a
    6.6 percent increase in spam since August.
--  Japan had the lowest spam rate with 27.1 percent. Germany also saw a
    sharp decrease of 10.2 percent in spam rates in the last month, marking a
    quarterly decline of 6.63 percent
--  India still remains the region most affected by viruses with 1 in 53
    emails containing a virus. The largest rise in virus activity was observed
    in the Netherlands where levels rose by 0.2 percent, from 1 in 750.1 emails
    in August to 1 in 303.3 emails in September.
    

Information provided by: Findarticles.com

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DUBLIN, Ireland — Research and Markets (http://www.researchandmarkets.com/reports/c69681) has announced the addition of "Stakeholder Opinions: Respiratory Syncytial Virus (RSV) - A Market Yet to Reach its Full Potential" to their offering.

RSV mostly causes upper respiratory tract infections (URTI), resulting in the common cold. However, in certain risk groups, RSV can cause more severe lower respiratory tract infections (LRTI) leading to bronchiolitis. These risk groups include elderly people, patients with underlying pulmonary or cardiac disease, premature infants, children under four years old and immunocompromised patients.

Scope of this title:

* Discusses disease background, providing insight in RSV epidemiology, etiology and symptoms

* Gives a breakdown of RSV (hospitalization) prevalence in the seven major markets

* Examines current diagnosis and treatment trends, providing physicians opinions

* Examines the RSV pipeline by type treatment, prophylaxis and vaccines, including a short discussion of each pipeline product

Highlights of this title:

* Some physicians do not value the importance of a correct RSV diagnosis, since there is no effective treatment available. Furthermore, the American Academy of Pediatrics does not recommend routine testing for RSV in bronchiolitis. However, there are reasons why proper diagnosis should be considered, and there is a range of tests available for that.

* The RSV market is currently dominated by MedImmunes Synagis, a prophylactic monoclonal antibody. As RespiGams successor, Synagis was first launched in 1998 and now has sales of around $750 million per RSV season. Due to its high costs though, Synagis is only prescribed to a very limited group of individuals.

* Although the most important unmet need in RSV is an effective treatment or vaccine, many companies have discontinued their developments in this field. Only two companies have an RSV treatment in clinical development (Novartis/Arrow Therapeutics and Alnylam) and MedImmune dominates the limited vaccine development.

Reasons to order your copy:

* Gain insight into the issues of current diagnosis and treatment for RSV through key opinion leader comments

* Review the unmet needs and the clinical and commercial factors driving new product decisions

* Identify the opportunities and threats presented by the RSV pipeline and predict the future shape of the market

Report Breakdown

Chapter 1 - Executive Summary
Chapter 2 - Disease Background
Chapter 3 - Diagnosis
Chapter 4 - Current Treatment And Prevention Option
Chapter 5 - Future Trends

 Appendix A - Bibliography
 Appendix B - Commercially Available Antigen Detection Assays

For more information visit http://www.researchandmarkets.com/reports/c69681

Source: Datamonitor

COPYRIGHT 2007 Business Wire
COPYRIGHT 2008 Gale, Cengage Learning

Information provided by: Findarticles.com

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Dutch biotechnology
company Crucell N.V. (Euronext, NASDAQ: CRXL, Swiss Exchange: CRX)
today announced the discovery of a set of human monoclonal antibodies
against H5N1. These results, demonstrating the potential of human
monoclonal antibodies for pandemic preparedness, were presented today
at the 5th International Bird Flu Summit held in Las Vegas, Nevada.

A total of twenty one human monoclonal antibodies were discovered.
These were found to be able to neutralize the H5N1 virus of avian
influenza, which currently presents a global threat. The most potent
of the antibodies was shown to neutralize the broadest range of H5N1
strains that have emerged between 1997 and 2004. This antibody may
therefore provide a powerful tool in pandemic preparedness. In
addition, this antibody prevents flu, in pre-clinical models, when
given twenty four hours before a challenge with a lethal dose of
highly pathogenic H5N1 virus. When given three days after infection,
it also was shown to prevent death and cure the disease.

“Our discovery of potent human monoclonal antibodies against a number
of different H5N1 pandemic flu types, provide proof of concept that
antibodies are a serious alternative to vaccination or antiviral
treatment”, said Dr. Jaap Goudsmit, Chief Scientific Officer of
Crucell. “What is most encouraging is the fact that these antibodies
are not only able to prevent infection, but also open the possibility
to treat infected individuals. Treatment with this antibody provides
an instantaneous antiviral response, which is an advantage over the
delayed immune response after (prepandemic) vaccination.”

The set of monoclonal antibodies, which was produced by Crucell
researchers using phage display and Crucell PER.C6® technology,
showed the potential to neutralize distinct H5N1 viruses,
A/Vietnam/11994/04, A/Hong Kong/213/03 and A/Hong Kong/156/97. The
antibodies apparently recognize a part of the viral membrane protein
that is present among all H5N1 viruses tested. The most potent
neutralizing antibody was tested in pre-clinical models for the
ability to protect against infection with the highly pathogenic
A/Hong Kong/97 H5N1 virus and was also tested for its ability to stop
the development of the disease caused by this virus. When the
monoclonal antibody was given in a pre-clinical model, one day prior
to infection with the H5N1 virus, it resulted in full protection
against infection. Treatment with the antibody up to three days after
infection, resulted in 100% survival and cure of the disease.

About Pandemic Influenza

Influenza is a highly infectious virus which spreads easily from
person to person. In a pandemic, a new and more virulent virus
infectious for humans arises with the potential to cause severe
disease and high mortality. H5N1 Viruses isolated from wild and
domestic birds and from humans since the outbreaks in Hong Kong
separate in distinct genetic groups (clade and subclades) of closely
related viruses. Clade 1 virus circulated in Cambodia, Thailand and
Viet Nam and caused infections in humans in 2004 and 2005. Clade 2
viruses circulated in China and Indonesia in 2003 -2004 and spread to
the Middle East, Africa and Europe in 2005 and 2006.

About Crucell

Crucell N.V. (Euronext, NASDAQ: CRXL; Swiss Exchange: CRX) is a
biotechnology company focused on research, development and worldwide
marketing of vaccines and antibodies that prevent and treat
infectious diseases. Its vaccines are sold in public and private
markets worldwide. Crucell’s core portfolio includes a vaccine
against hepatitis B, a fully-liquid vaccine against five important
childhood diseases, and a virosome-adjuvanted vaccine against
influenza. Crucell also markets travel vaccines, such as the only
oral anti-typhoid vaccine, an oral cholera vaccine and the only
aluminium-free hepatitis A vaccine on the market. The Company has a
broad development pipeline, with several Crucell products based on
its unique PER.C6® production technology. The Company licenses this
and other technologies to the biopharmaceutical industry. Important
partners and licensees include DSM Biologics, sanofi aventis, GSK and
Merck & Co. Crucell is headquartered in Leiden (the Netherlands),
with subsidiaries in Switzerland, Spain, Italy, Sweden, Korea and the
US. The Company employs over a 1000 people. For more information,
please visit www.crucell.com .

Forward-looking statements

This press release contains forward-looking statements that involve
inherent risks and uncertainties. We have identified certain
important factors that may cause actual results to differ materially
from those contained in such forward-looking statements. For
information relating to these factors please refer to our Form 20-F,
as filed with the U.S. Securities and Exchange Commission on June 13,
2007, and the section entitled “Risk Factors”. The Company prepares
its financial statements under generally accepted accounting
principles in the United States (US GAAP) and Europe (IFRS).

Information provided by: Findarticles.com

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100-Fold Dosage Reduction Still Fully Effective in Preventing Mortality

NEW YORK — SIGA Technologies, Inc. (NASDAQ: SIGA) today announced that its lead smallpox drug, ST-246, has passed another milestone by demonstrating 100% protection against death in cynomolgus monkeys showing signs of infection with monkeypox virus as part of a primate trial conducted at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID). The study included a wide range of doses, all of which successfully prevented death, including a dose that was one one-hundredth of the dose given in prior primate trials. The amount of virus introduced into each animal is usually fatal absent ST-246 (all of the control subjects died), and all of the animals had developed fever and skin lesions prior to the administration of SIGA’s drug.

"We are particularly pleased with the results of this study," said Dr. Dennis E. Hruby, Chief Scientific Officer of SIGA. "The timing of drug administration in this study correlates to a late stage in the disease progression in humans. With this new information, we believe that ST-246 can be used to prevent mortality in humans even several days after elaboration of symptoms. Furthermore, the protection afforded by modest drug doses further enhances our confidence that a protective level in humans can be achieved with a low risk of toxicity," Hruby concluded.

In the study, once-daily, oral administration of ST-246 beginning 72 hours after infection protected cynomolgus monkeys from death following intravenous dosing with a lethal dose of monkeypox virus. ST-246 reduced lesion formation, reduced viral load and prevented death in all animals with no obvious toxicity. Furthermore, the test included a range of dosages (100 mg/kg to 3 mg/kg) of ST-246, and all were effective. The U.S. Department of Defense’s Defense Threat Reduction Agency under the supervision of Dr. John Huggins, Chief of the Viral Therapeutics Branch, USAMRIID, funded and ran the study.

Commenting on the study, Dr. Huggins stated, "This is the first drug candidate that successfully treated monkeypox in our primate models after the onset of pox lesions, the most likely time that patients would be diagnosed with disease. We are encouraged and believe that this drug candidate may represent a practical solution to treating disease in a wider population where rapid laboratory-based diagnosis is not practical."

Smallpox is considered one of the most significant biowarfare threats. The federal Centers for Disease Control and Prevention (CDC) classifies variola, the virus that causes smallpox, as a "Category A" (highest level threat) bioterrorism agent. Smallpox is readily transmitted between humans, it has significant mortality rates, and the population is no longer vaccinated against it. Mass immunizations of the general population using the current live vaccine can be problematic, as there are known complications affecting some individuals, which may include encephalitis, myocarditis, and death. Immunocompromised individuals receiving this vaccine are at particular risk from a systemic infection. At this time, there is also no approved treatment for smallpox.

The Department of Homeland Security has designated smallpox a "material threat" to our national security, which renders ST-246 eligible for purchase for the Strategic National Stockpile under Project Bioshield.

SIGA previously announced that ST-246 has been shown to be safe to administer to humans as a once-a-day pill. ST-246 has also demonstrated 100% disease protection in several mouse models of infection, which results SIGA will use, along with additional tests yet to be completed, to fulfill the U.S. Food and Drug Administration’s "Animal Efficacy Rule." In December 2005, the FDA granted "fast-track" status to ST-246.

About SIGA Technologies, Inc.:

SIGA is applying viral and bacterial genomics and sophisticated computational modeling in the design and development of novel products for the prevention and treatment of serious infectious diseases, with an emphasis on products for biological warfare defense. SIGA believes that it is a leader in the development of pharmaceutical agents and vaccines to fight potential biowarfare pathogens. In addition to smallpox, SIGA has antiviral programs targeting other Category A pathogens, including arenaviruses (Lassa fever, Junin, Machupo, Guanarito, Sabia, and lymphocytic choriomeningitis), dengue virus, and the filoviruses (Ebola and Marburg). SIGA’s product development programs also emphasize the increasingly serious problem of drug-resistant bacteria. For more information about SIGA, please visit SIGA’s Web site at www.siga.com.

About the Defense Threat Reduction Agency (DTRA):

DTRA is an agency of the U.S. Department of Defense that safeguards America and its allies from weapons of mass destruction by providing capabilities to reduce, eliminate and counter the threat and mitigate its effects. DTRA headquarters is located at Fort Belvoir, Virginia, and it also operates field offices worldwide. The DTRA has identified an orthopox therapeutic as a critical need in its ongoing threat reduction efforts.

Information provided by: Findarticles.com

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Britain is braced for the spread of another devastating animal disease after the first case of the bluetongue virus was confirmed in this country, the latest blow to Britain’s farmers after months of misery and hardship.

The deputy chief veterinary officer, Fred Landeg, confirmed that the strain of the virus detected in a highland cow at a rare breeds farm near Ipswich was the same BTV8 strain that has swept across Germany France and the Netherlands, causing huge losses in livestock. Farmers in Britain can only wait and hope that the infection remains an isolated case.

The disease which originated in Africa is spread by midge bites and there is currently no vaccine available. There are fears that if midges can survive, as a result of climate change, the impact of bluetongue could be even worse than the latest outbreak of foot-and- mouth disease for Britain’s farmers. The exclusion zones could be far wider, if an outbreak is confirmed in the area, to try to limit the spread of the infected midges.

Last night, to add to farmers’ woes, the Department for Environment, Food and Rural Affairs (Defra) announced a new 3km control zone around a farm at Petersfield, Hampshire, following a seventh suspected outbreak of foot-and-mouth since the crisis began on 3 August.

Farmers are desperately hoping that a cold snap will kill the midges that carry the bluetongue virus. Peter Kendall, the National Farmers’ Union president, said that after floods and foot and mouth, the latest disease to hit farmers was bound to cause further hardship.

Measures which may be taken include spraying animals with repellents, keeping animals under cover, and killing midge larvae on middens. But unlike foot-and-mouth disease, there is no point in culling cows on the basis of suspicion.

The highland cow that became the first animal in Britain to contract bluetongue has been culled, and further tests were being carried out at Baylham House rare breeds farm near Ipswich to see if other animals including llamas, sheep and cattle were infected. The Storer family, who own the farm, spoke about the emotional rollercoaster ride they have endured in the past traumatic week.

They were given the all-clear for foot-and-mouth after their highland cow - a great favourite with visitors - showed symptoms, but were later told she had bluetongue.

The symptoms include swelling in joints, difficulty in breathing, and discharges from the nostrils. The virus is usually fatal in sheep but it cannot be passed to humans. British vets have been watching the wind and weather patterns but warned ministers some weeks ago that it was likely that the virus would arrive in England from the Continent.

The Prime Minister chaired a meeting of Cobra, the Cabinet Office emergency committee, to discuss the latest possible outbreak of foot- and-mouth disease before heading to Bournemouth for the Labour Party conference. He was told when he reached his hotel on Saturday night that the bluetongue case had been confirmed. The chief veterinary officer, Debby Reynolds said: “It remains important farmers maintain vigilance for this disease and report any suspect cases, particularly as signs may be similar to foot-and-mouth.

The Institute for Animal Health, at Pirbright in Surrey - which was suspected as the source of the foot-and-mouth outbreak - has been working on combating bluetongue.

leading article, page 34

Outbreaks in northern Europe

–NETHERLANDS: First country in northern Europe to report a case of bluetongue (August 2006). The disease subsequently spread, with the Netherlands, Germany and Belgium hardest hit. Despite restrictions on livestock movements, there have been 1,891 outbreaks of bluetongue this year.

GERMANY: Bluetongue reached Germany in April and, by the end of August 856 outbreaks had been reported, although recent estimates have put the figure closer to 1,400. A total of 9,856 animals have tested positive for the virus, of which 2,034 died.

–BELGIUM: The entire country is considered an infected zone and 20km restrictions have been in place across the country. There have been 2,195 outbreaks of the disease this year, according to the European Commission.

–FRANCE: Restrictions on the movement of livestock have been imposed.More than 200 cases of the disease have been reported.

Copyright c 2007 Independent Newspapers UK Limited. All rights
owned or operated by The Independent.
Provided by ProQuest Information and Learning Company. All rights Reserved.

Information provided by: Findarticles.com

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Bluetongue virus threat to UK

September 23, 2007

By Jonathan Owen,Geoffrey Leanand Ruth Elkins

Britain’s farmers are facing their greatest ever crisis this weekend. A second virulent animal disease is threatening to sweep through the country at the most critical time of year.

Two teams of government vets worked through last night, frantically analysing hundreds of blood samples, after Britain’s first case of the lethal bluetongue disease was found in an elderly cow on a children’s “petting” farm near Ipswich yesterday. Professor Peter Mertens, who is leading the investigations at the Institute for Animal Health at Pirbright, told The Independent on Sunday late last night that “the door is open” for repeated infections of the disease, which has no known cure and can kill 70 per cent of the animals it strikes.

Earlier yesterday, the Government’s chief vet, Debby Reynolds, said another farm - the sixth in less than two months - had been found to be infected with foot and mouth at Beaumont Farm, Old Windsor

The Prime Minister, Gordon Brown, had barely emerged from an emergency meeting of the Cobra crisis committee on the foot-and- mouth developments when he was told of the latest plague to hit his premiership. The infected cow is to be slaughtered.

The crises threaten to hit farmers with a deadly double whammy at a vulnerable time. Sheep farmers make almost their entire annual income by sending their animals for slaughter during the next few weeks, and livestock has to be brought down from the hills to their winter pastures.

Bluetongue - whose imminent arrival in Britain was exclusively predicted by the IoS last month - after it had spread northwards in Europe as temperatures have increased due to global warming - is more deadly than foot and mouth, and is even more difficult to control. It is spread by midges, which can carry it over far greater distances, causing far greater swathes of the countryside to be sealed off.

Restrictions on animal movements have to be imposed for 150km around an outbreak of bluetongue, 15 times more than for foot and mouth. Meat exports would be banned, and experts fear it could be two years before they were given the all clear again.

The Department for the Environment, Food and Rural Affairs was trying to calm fears by saying that that it could not be certain that there had been an outbreak of bluetongue until another animal was found to be infected.

It has estimated that the plague could affect 10 million sheep and nine million cattle in Britain. It added that “UK sheep breeds are particularly susceptible, and have no immunity”. No vaccine exists against the strain of the disease (BTV8) most likely to have arrived in Britain.

Last night Professor Mertens, who is head of the Arbovirus Research Group at the Institute for Animal Health, broke off from his investigations to tell the IoS that his team was testing “at least 300 or 400 blood samples” taken from livestock around the Ipswich area to identify the strain of the virus, and to see whether it has spread.

He said: “On the Continent, the disease has gone ballistic; there have been thousands of outbreaks in Europe in recent weeks. Everything is pointing to this [the case in Britain] having come from an infected midge blown in from the Continent. The Met Office is working overnight to make predictions on wind movement to identify the areas at greatest risk.”

But he added: “Midges don’t normally travel on their own, but in large numbers. The discovery of an infected animal proves that the door is open and it’s now a question of how many midges came through it.”

Q&A: all about the deadly insect-borne disease

What is bluetongue?

Bluetongue, known as BTV (one of its 24 variants is modelled right), is an insect-borne viral disease that affects ruminants, including sheep, cattle, deer and goats. It is transmitted by the ‘Culicoides imicola’ midge. Sheep are most at risk from the disease, which gets its name from the way that sheep’s tongues can turn blue as a result of pressure from the intense swelling. Symptoms include swelling of the neck, ulceration of the mouth, nose and eyes, and lameness. It is most commonly seen in late summer and autumn.

Where has it come from?

Discovered in South Africa, bluetongue has since been recognised in most countries in the tropics and sub-tropics. Since 1999 there have been outbreaks in Greece, Italy, Corsica and the Spanish Balearic Islands, and cases in Germany, Belgium, the Netherlands, France, Croatia, Luxembourg, Bulgaria, Kosovo, Macedonia and Yugoslavia.

How does it spread?

Bluetongue can’t be transmitted directly between animals. The virus is spread when a midge bites an infected animal and then bites an uninfected animal. Defra says the likelihood of transmission by unhygienic practices can’t be excluded.

Is it deadly?

Yes, although it is harmless to humans. The most virulent strain of the virus can kill up to 70 per cent of infected sheep in two weeks.

Why has it arrived now?

Since the virus can survive on the same latitude as southern England, all we need is for wind to carry the midges across the Channel.

Information provided by: Findarticles.com

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PARIS (AFP) — Scientists in Singapore say they have devised a mini-lab capable of identifying the H5N1 bird flu virus in less than 30 minutes, in what they believe could be a breakthrough in efforts to shore up defences against any flu pandemic.

Other commercially available tests take from several hours to a matter of days to deliver results and are many times more expensive, the inventors report in the journal Nature Medicine.

One of the big tasks in a putative pandemic of bird flu would be to identify and isolate infected people to stop them spreading the virus to others.

In the best-case scenarios, an outbreak can be halted if it does not spread beyond the first 20 cases or if it is contained within three weeks after the first case emerges.

So the ability to screen people swiftly at the point of outbreak and at migratory …


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Information provided by: Findarticles.com

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