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Archive for July, 2007

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<!DOCTYPE text PUBLIC "-//The Gale Group//DTD Mercury Version 1.0//EN" "Article.dtd">

<Text rich="yes"> <P> An international team of investigators has identified the first human antibodies that can neutralize different strains of the virus responsible for outbreaks of severe acute respiratory syndrome (SARS). </P> <XEB.p> To read the full text of this article, click here: <XEB.a href="http://www.nih.gov/news/pr/jul2007/nci-02.htm" style="external"> http://www.nih.gov/news/pr/jul2007/nci-02.htm </XEB.a> </XEB.p> </Text>

COPYRIGHT 2007 National Institutes of Health
COPYRIGHT 2007 Gale Group

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PARIS (AFP) — Three swans found dead in northeast France are being analysed to see if they carried the H5N1 strain of bird flu which can be fatal to humans, the agriculture ministry said Tuesday.

“First analyses have established a suspicion of bird flu. More tests are under way to see … if this is an infection with the H5N1 strain,” the ministry said.

Results will be known Thursday, and in the meantime measures have been taken to …


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"Network Effect" Leveraging More Than 40,000 Barracuda Spam Firewalls Across the Internet Augments "Zero-Hour" Protection

CAMPBELL, Calif. — Barracuda Networks, Inc., a leading provider of network security appliances, today announced Barracuda Real-Time Protection, a set of technologies that enable the Barracuda Spam Firewall to immediately block the latest virus, spyware, and other malware attacks as they emerge. Barracuda Real-Time Protection provides customers with industry-leading response times to email-borne threats by adding a third layer of antivirus protection to the Barracuda Spam Firewall.

"With the world’s largest installed base of more than 40,000 Barracuda Spam Firewalls in more than 80 countries, Barracuda Networks is uniquely positioned to detect early trends in email-borne threats," said Stephen Pao, vice president of product management for Barracuda Networks. "By combining this early detection capability with real-time response, the Barracuda Spam Firewall delivers industry-leading virus and malware protection to organizations of all sizes."

Unique Message Fingerprints Lead to Zero-Hour Identification and Blocking

Unlike traditional antivirus solutions which perform analysis against data stored on a single system, Barracuda Real-Time Protection is based on data collected from thousands of global honeypots and Barracuda Spam Firewalls across the Internet. This data consists of binary signatures, or ‘fingerprints,’ for message components such as message bodies, email attachments and inline images. When unknown fingerprints are detected, the Barracuda Spam Firewall submits these fingerprints in real-time to Barracuda Central, an advanced technology center where engineers monitor the Internet for the latest threats and deploy solutions 24×7 to stop them.

Once Barracuda Central engineers identify a potential virus or malware outbreak based on the frequency, diversity of sources and the metadata about the message itself, Barracuda Central validates the hypothesis by collecting samples of suspect emails from Barracuda Spam Firewalls around the world that have opted-in to data collection. Immediately upon virus or malware classification, Barracuda Central responds to any Barracuda Spam Firewalls submitting the corresponding fingerprints with an instruction to immediately block the message, thus stopping the attack in real time.

"While automatic Energize Updates have always kept the Barracuda Spam Firewall ahead of massive threat proliferation, Barracuda Real-Time Protection adds an additional level of security during the earliest stages of a new outbreak," said Pao.

After identifying new virus and other malware outbreaks, Barracuda Central updates the spam and virus definitions downloaded by the Barracuda Spam Firewall through Energize Updates. Upon the next Energize Update, the Barracuda Spam Firewall can block the virus or spam variants associated with the new outbreak via the Barracuda Spam Firewall’s traditional antivirus protection layers.

Pricing and Availability

Barracuda Real-Time Protection technology is immediately available to all Barracuda Spam Firewall customers running firmware release 3.5 or later. All Barracuda Spam Firewall customers with current Energize Updates subscriptions may upgrade to the latest firmware release at no additional charge. For new customers, Barracuda Spam Firewall pricing varies by model and starts at $899 in the U.S. with no per user licensing fees. International pricing varies by region.

About the Barracuda Spam Firewall

The Barracuda Spam Firewall is available in seven models and supports from 50 to 30,000 active users with no per user licensing fees. Its architecture leverages 12 defense layers: denial of service and security protection, rate control, IP analysis, sender authentication, recipient verification, virus protection, policy (user-specified rules), Fingerprint Analysis, Intent Analysis, Image Analysis, Bayesian Analysis, and a Spam Rules Scoring engine. In addition, the entire Barracuda Spam Firewall line features simultaneous inbound and outbound email filtering with the inclusion of sophisticated outbound email filtering techniques, such as rate controls, domain restrictions, user authentication (SASL), keyword and attachment blocking, dual layer virus blocking, and remote user support for outbound email filtering. The Barracuda Spam Firewall’s layered approach minimizes the processing of each email, which yields the performance required to process millions of messages per day. For more information on the Barracuda Spam Firewall, visit http://www.barracuda.com/spam.

About Barracuda Networks, Inc.

Barracuda Networks is a leading provider of network security appliances for comprehensive email, Internet and IM protection. Its products protect over 40,000 customers around the world, including Adaptec, Caltrans, CBS, Georgia Institute of Technology, IBM, NASA, Pizza Hut, Union Pacific Railroad Company, and the U.S. Treasury Department. The Barracuda Spam Firewall and Barracuda Spam Firewall - Outbound protect organizations against spam, viruses, and violations to email security policy. The Barracuda Web Filter offers comprehensive content filtering and complete network protection against spyware, malware and viruses. The Barracuda IM Firewall is the only all in one gateway solution for IM traffic management and security. The Barracuda Load Balancer offers easy to configure, secure and comprehensive IP network traffic management across multiple servers. Barracuda Networks is a privately held company with headquarters in Campbell, California. Barracuda Networks has offices in eight international locations and distributors in over 80 countries. More information is available at www.barracuda.com.

COPYRIGHT 2007 Business Wire
COPYRIGHT 2008 Gale, Cengage Learning

Information provided by: Findarticles.com

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M2 PRESSWIRE-2 July 2007-SoftScan: Spam on the rise again; June’s spam and virus statistics from SoftScan(C)1994-2007 M2 COMMUNICATIONS LTD RDATE:02072007 London, UK - SoftScan announced today that spam levels are back up in the nineties, with 90.06 of email scanned during June classified as spam.

Spam levels fluctuated throughout the month and some days saw levels drop to 86, but SoftScan concludes that the most likely scenario is that there were just less customers in the spam shop on these days. "Changes in spam levels normally signal one of two things, either a …

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Invitrogen Improves HPV Test: Invitrogen Corp. of Carlsbad and German company Greiner Bio-One are partnering to improve the reliability of Bio-One’s test for the Human Papilloma Virus, which causes 70 percent of cervical cancer and can cause genital warts. Starting last month, Bio-One’s PapilloCheck contain …

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KUALA LUMPUR (AFP) — Malaysia will rename a newly-discovered bat-borne virus following an angry protest from the state it was named after, reports said Monday.

Malaysian and Australian scientists recently announced that they had discovered a virus believed to be carried by bats that causes serious respiratory illness in humans.

Malaysian health authorities decided to name it “Melaka virus” after it infected a family of four in southern Malacca state in March last year.

State officials objected, saying it was “an insult” and would harm the tourism industry in Malacca which is a popular destination for foreign visitors.

“We will rename the virus if we can as …


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M2 PRESSWIRE-2 July 2007-Kaspersky Lab: Netsky.q returns to top of virus chart(C)1994-2007 M2 COMMUNICATIONS LTD RDATE:02072007 Abingdon, UK - NetSky.q, the all-time leader for 2004 and 2005, has returned to head the virus Top 20 for June, according to information security software vendor, Kaspersky Lab.

Hot on its heels is a worm from an equally old family, Bagle.gt. Last month’s leader, NetSky.t, slipped to third place. Arguably the most noteworthy event this month was the disappearance of May’s rabble-rouser, Sober.aa. This virus re-appeared after a six-month stint in the …

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Aside from discrimination against dogs, there’s a story here about how antivirus can help to protect you from unknown threats. If I walk up to a restaurant with a Catahoula Leopard Dog, the odds are that nobody in the restaurant has ever seen this breed of clog before. So, why won’t they let me in with an animal they have never seen before? The answer is heuristics.

Heuristics use rules to solve problems. Perhaps you have never seen a Catahoula Leopard dog, but if you did you would recognize it as a dog. The animal looks like several other animals you have seen that are also dogs. …

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Several sub-Saharan militaries have large percentages of troops with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome. With the arrival of avian influenza in Africa, the potential exists that some of those soldiers might also become infected with H5N1, the virus responsible for the disease. Two possible scenarios have been postulated regarding how such a coinfection of HIV and H5N1 might present. (1) Soldiers already weakened by HIV/acquired immunodeficiency syndrome rapidly succumb to H5N1. The cause of death is a “cytokine storm,” essentially a runaway inflammatory response. (2) The weakened immune system prevents the cytokine storm from occurring; however, H5N1 is still present, replicating, and being shed, leading to the infection of others. A cytokine storm is particularly dangerous for individuals of military age, as evidenced by the large number of soldiers who died during the 1918 influenza epidemic. If large numbers of sub-Saharan soldiers suffer a similar fate from avian influenza, then military and political instability could develop.

Introduction

A vlan Influenza, also known as bird flu, is caused by viruses that normally infect only birds and, less frequently, pigs.1 Although the viruses are highly species specific, they have on rare occasions crossed the species barrier to infect humans. Such is the case with avian influenza A (H5N1), the present cause of much concern. The World Health Organization (WHO) reports that human infections caused by direct transmission of avian influenza viruses from birds, H5N1, is responsible for the largest number of cases of severe disease or death.2 A devastating pandemic could ensue if the virus eventually acquires the ability to be easily transmitted among humans.3

This increased transmissibility might occur through an antigenie shift, where two different influenza strains genetically recombine to form a new subtype. In the past, this mechanism, involving viruses other than H5N1, has been responsible for several major influenza outbreaks, including the Asian (H2N2) and Hong Kong (H3N2) influenza pandemics of 1955 and 1968, respectively.4

The relatively recent arrival of H5N1 in Africa, where human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) is endemic in many countries, raises both concerns and uncertainties, including those of a military nature. Currently, it is not known what the outcome would be if people with HIV/AIDS became coinfected with H5N1. Because many sub-Saharan African militaries have large percentages of soldiers with HIV/AIDS, especially in comparison with their corresponding civilian populations, questions exist regarding what effect avian influenza might have on such troops, as well as their comrades, and whether it could affect military capabilities.5

If large numbers of sub-Saharan troops are killed or incapacitated by the avian flu, then it is possible that some countries would suffer internal instability. Other countries might take advantage of such situations, with the result that regional conflicts could erupt. Besides the enormous human toll that could result from the fighting, important exports to the United States, including oil, could be significantly disrupted.

With several peacekeeping missions involving African troops, there is an additional concern that they could be responsible for disseminating H5N1 to other regions. Their close contact with civilian populations in host countries, and the potentially large number of subsequent fatalities from the disease, could cause instability in countries originally spared from avian influenza.

By examining medical, military, and political scenarios that might occur if large numbers of African troops become coinfected with HIV/AIDS and H5N1, it is hoped that measures can be developed to mitigate or even prevent the worst possible outcomes. In an era of increasing globalization, providing effective interventions would probably benefit not only the countries of Africa but also other nations, including the United States.

Geographic Spread of the Disease

H5N1 has been significantly more widespread in poultry and wild birds than in people. The virus possibly arose in birds in southern China before 1997.6 By mid-2003, large numbers of birds in Asia were infected, although this initially went undetected and unreported. The disease continued to spread among birds, and it is now considered endemic in many parts of Vietnam and Indonesia, as well as some areas of Cambodia, China, Thailand, and possibly the Lao People’s Democratic Republic. Other countries in Asia and Europe have also reported infected poultry and/or wild birds, although not to the extent that the disease would be considered endemic. Three countries, namely, Japan, the Republic of Korea, and Malaysia, had outbreaks of H5N1 in poultry but were able to control them, at least initially, through methods such as destroying the birds. Indeed, killing infected poultry is considered one of the cornerstones in the strategy to combat avian influenza. Because the disease appears to be transmitted to people via prolonged contact with H5N1positive birds, methods such as destroying these animals possibly help to prevent the spread of disease to other flocks as well as to humans. It should be noted that, although birds at least are a large reservoir of the virus and likely are a direct vector for human infection, animals such as dogs and cats, which feed on infected birds, are being considered as possible intermediate mammalian vectors, which is why South Korea, in attempting to control an outbreak of H5N1, plans to cull them.7

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ViroPharma, Inc., Exton, PA, announced the FDA has granted fast track designation for HCV-796 for the treatment of hepatitis C virus infection (HCV). The company says VCV-796 is a unique orally dosed non-nucleoside hepatitis C viral polymerase inhibitor that interferes with the replication of HCV. The drug is currently undergoing Phase 2 evaluation and is being co-developed with Wyeth Pharmaceuticals, a division of Wyeth, Collegeville, PA.

Under the FDA Modernization Act of 1997, fast track designation may potentially expedite the review of a drug that is intended for the treatment of a serious life-threatening condition and demonstrates the potential to address an unmet medical need for such a condition. Fast track designation allows the FDA to accept, on a rolling basis, portions of a marketing application for review prior to the completion of the final registration package. The designation does not guarantee approval or expedited approval of any application for the product.

Currently, there is no specific antiviral agent directed against HCV that is commercially available, and no vaccine for prevention of HCV infection.

Contact: William Roberts - Phone: (610) 321-6288; Web site: www.viropharma.com

COPYRIGHT 2007 Transplant Communications, Inc.
COPYRIGHT 2008 Gale, Cengage Learning

Information provided by: Findarticles.com

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